The XPBM-1 prototype flying-boat patrol bomber was originally ordered by the US Navy in 1936. Before it was built, a quarter-size prototype (Model 162A) was constructed and flown. The full-size aircraft was flown for the first time in February 1939.

The production PBM-1 - fitted with two 1,192 kW Wright R-2600-6 radial engines, a dihedral tail and retractable wingtip floats - was ordered in 1938 and 20 of these went into Navy service in 1941. A single XPBM-2 was ordered at the same time as a long-range version specially strengthened for catapult take-off.

The PBM-3, with two 1,267kW Wright R-2600-12 engines, was ordered in quantity in 1940 and deliveries began in 1942. In this version the crew was increased from seven to nine, the armament was revised and the fuel capacity increased. The retractable wingtip floats of the PBM-1 were replaced by fixed floats. In 1942 the PBM-3 was adopted also as a naval transport carrying 20 passengers or 3,629-4,082kg of cargo (PBM-3R). Twenty-six PBM-3B patrol bombers were also used by RAF Coastal Command, delivered under Lend-Lease. At the end of the war a specialised anti-submarine version was also developed as the PBM-3S.

The final two production versions of the Mariner were the PBM-5 and PBM-5A, powered by 1,565kW R-2800-22 and R-2800-34 engines respectively. The last PBM-5A was delivered to the US Navy in April 1949. This version was basically an amphibious version of the PBM-5 and ended its career as a general utility aircraft.